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Literature summary extracted from

  • Svoboda, E.; Schneider, A.E.; Sandor, N.; Lermann, U.; Staib, P.; Kremlitzka, M.; Bajtay, Z.; Barz, D.; Erdei, A.; Jozsi, M.
    Secreted aspartic protease 2 of Candida albicans inactivates factor H and the macrophage factor H-receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) (2015), Immunol. Lett., 168, 13-21 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.23.24 complement component C3b + H2O Candida albicans
-
 ?
-
 ?
3.4.23.24 complement component C4b + H2O Candida albicans
-
 ?
-
 ?
3.4.23.24 complement component C5 + H2O Candida albicans
-
 ?
-
 ?
3.4.23.24 factor H + H2O Candida albicans the enzyme cleaves and inactivates factor H, diminishing its complement regulatory activity ?
-
 ?
3.4.23.24 macrophage factor H-receptor CR3 + H2O Candida albicans the enzyme cleaves and inactivates macrophage factor H-receptor CR3 ?
-
 ?
3.4.23.24 macrophage factor H-receptor CR4 + H2O Candida albicans the enzyme cleaves and inactivates macrophage factor H-receptor CR4 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.23.24 Candida albicans
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.23.24 complement component C3b + H2O
-
 Candida albicans ?
-
 ?
3.4.23.24 complement component C4b + H2O
-
 Candida albicans ?
-
 ?
3.4.23.24 complement component C5 + H2O
-
 Candida albicans ?
-
 ?
3.4.23.24 factor H + H2O the enzyme cleaves and inactivates factor H, diminishing its complement regulatory activity Candida albicans ?
-
 ?
3.4.23.24 macrophage factor H-receptor CR3 + H2O the enzyme cleaves and inactivates macrophage factor H-receptor CR3 Candida albicans ?
-
 ?
3.4.23.24 macrophage factor H-receptor CR4 + H2O the enzyme cleaves and inactivates macrophage factor H-receptor CR4 Candida albicans ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.23.24 SAP2
-
 Candida albicans
3.4.23.24 secreted aspartic protease 2
-
 Candida albicans